NATURAL VARIATION IN THE CONSEQUENCES OF GENE OVEREXPRESSION AND ITS IMPLICATIONS FOR EVOLUTIONARY TRAJECTORIES

Natural variation in the consequences of gene overexpression and its implications for evolutionary trajectories

Copy number variation through gene Dryer Door Seal or chromosome amplification provides a route for rapid phenotypic variation and supports the long-term evolution of gene functions.Although the evolutionary importance of copy-number variation is known, little is understood about how genetic background influences its tolerance.Here, we measured fit

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Recent Issues in Varicella-Zoster Virus Latency

Varicella-zoster virus (VZV) is a human herpes virus which causes varicella (chicken pox) as a primary infection, and, following a variable period of latency in neurons in the peripheral ganglia, may reactivate to cause herpes zoster (shingles) as well as a variety of neurological syndromes.In this overview we consider some recent issues in alphahe

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